| Autor: |
Ali, Saja Mohammed Hussein, Alali, Muqdam Mahdi Mohammad Ali, Ahmed, Luma Majeed |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2022, Vol. 2547 Issue 1, p1-7, 7p |
| Abstrakt: |
The flower-like hierarchical polyoxometalate (POM) - Dopamine nanostructure has successfully been synthesized in a ratio (1:1) from (POM) as Phosphotungstic (PTA) acid (kegging-type) with Dopamine in Tris-HCl tris [aminomethane] at pH [10.00-8.8] and then aging using Microwave technique for 12 min, the result color powder was greenish-yellow. The SEM analysis revealed that the prepared nanostructure had a like-flower nanostructure that appropriate shapes for applied as Furosemide drug delivery in vitro. The loading of Furosemide on this prepared nanostructure surface was built at 4 h. Both prepared samples were subjected to XRD analysis, which revealed that the nanostructure and loaded Furosemide drug on its surface had been successfully prepared. The amount of Furosemide drug-loaded and released was calculated using (UV/Vis) spectroscopy at 270 nm The releasing of Furosemide drug was applied in acidic and neutral mediums and deduced that the maximum efficiency for releasing appeared at neutral medium. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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