| Abstrakt: |
Vitamin D deficiency has been contributed to type 2 diabetes and Metabolic Syndrome progression. The aim of this study was to see if there was an association between vitamin D and glucose, blood pressure, kidney biomarkers, lipid profiles in Iraqi type 2 diabetes patients. Also, compare the anthropometric and clinical parameters of diabetes in addition to vitamin D level between T2DM patients and healthy controls. This case-control study was conducted with 100 diabetic patients who visited The National Diabetes Center in Baghdad/Iraq. 100 healthy controls of students at Al-Nahrain University in Baghdad/Iraq. The period of study was from October 2018 to June 2019. After recording demographic and anthropometric factors, fasting blood and serum samples was taken to measure of blood glucose, HbA1c, Urea, creatinine, lipid profile and 25-hydroxyvitamin D3 (25-OHD3). The results showed that statistically significant differences between T2DM patients and healthy controls in BMI, FBG, HbA1c, 25(OH) D, and lipid profile levels (P≤ 0.005). The blood urea levels increase significantly in diabetes patients more than controls (P≤ 0.05). Vitamin D inversely associated with FBG (r = -0.236, P=0.028) and HbA1c (r=−0.303, P=0.0045). Vitamin D level, HDL and blood urea decreased significantly in T2DM patient's more than healthy controls. Furthermore, BMI, lipid profile, FBG and HbA1c increased significantly in T2DM patients higher than healthy controls. There is an inverse relationship between FBG and HbA1c concentration and the level of 25 (OH)-D in Iraqi patients with diabetes mellitus type 2. [ABSTRACT FROM AUTHOR] |
