| Autor: |
Pitale, Shailesh, Sahasrabuddhe, Anagha, Gandhi, Pramod, Joshi, Prashant, Sakhare, Ajay, Balankhe, Nikhil, Khobragade, Shankar, Sengupta, Shantanu, Ambulkar, Sunil, Ganeriwal, Mukund, Shembalkar, Jayashri, Naidu, Sanjay |
| Předmět: |
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| Zdroj: |
Indian Journal of Endocrinology & Metabolism; Sep/Oct2022, Vol. 26 Issue 5, p471-477, 7p |
| Abstrakt: |
Objective: This study was done to analyse the demographic profile and presentation of diabetes in Central India. Design: Data was collected for this cross‑sectional study from an electronic diabetes registry from 2014 to 2019. Demographic details, patient history and presence or absence of co‑morbid conditions, duration of diabetes, age of onset of diabetes, drug history, personal history, presence of micro and/ or macrovascular complications and investigations done were obtained. Statistical Analysis: The association between each factor and the outcome was studied in terms of prevalence ratio (PR) using the R‑3.0.0 programming (R Foundation for Statistical Computing, Vienna, Austria) language. Statistical significance was evaluated at a 5% level. Results: Among 12,434 patients, 54.95% were below 50 years and 45.05% were above 50 years. 50.21% were females and 49.79% were males. The mean age was 47.49 ± 14.78 years and the mean body mass index (BMI) was 26.85 ± 5.19 kg/m² with 62.29% of obese patients (>25 kg/m² ). The mean overall duration of diabetes was 7.64 ± 7.63 years. Mean Glycosylated Haemoglobin (HbA1c) in patients <=50 years was 8.60 ± 2.63 and 8.90 ± 1.91 for over 50. 65.59% had uncontrolled blood sugars. 25.19% of patients had hypertension and 18.1% had dyslipidaemia. Coronary artery disease (CAD), nephropathy, neuropathy and retinopathy were observed in 21.49%, 9.60%, 33.65% and 14.65%, respectively. The adjusted PR of cardiovascular disease (CVD) was 5.374 times higher for patients over 50 (P < 0.0001); 3.775 times higher for males(P < 0.0001), 1.64 times higher for patients with BMI >25 kg/ m² (P < 0.0001) and 3.643 times higher in hypertensive cases (P < 0.0001). Similar associations were observed with nephropathy, neuropathy and retinopathy. Conclusion: From a large population study on diabetes, it was found a majority of the type 2 diabetes mellitus (T2DM) cases (65%) are sub‑optimally controlled with HbA1c levels. Also, microvascular complications were related to the sub‑optimal glycaemic control, but not the macro‑vascular complications. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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