| Autor: |
Loganovsky, K., Fedirko, P., Marazziti, D., Antypchuk, K., Babenko, T., Masiuk, S., Garkava, N., Loganovska, T., Dorichevska, R., Kuts, K., Petrchuk, I., Kreinis, G. |
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| Zdroj: |
European Psychiatry; 2022 Special issue S1, Vol. 63, pS436-S437, 2p |
| Abstrakt: |
Introduction: Radiation accidents, long-term space flights and interventional radiological procedures may induce detrimental brain and ophthalmic effects. Objectives: The aims of our studies are at exploring long-term potential brain and ophtalmic effects of ionizing radiation (IR) in a group of Chornobyl clean-up workers (liquidators). Methods: The randomized sample (n=198) of Chornobyl catastrophe clean-up workers (liquidators) and 110 non-exposed control subjects were examined with a battery of neuropsychiatric, psychometric, neuropsychological, psychophysiological methods, including visual sensory and cognitive evoked potentials. The cohort ophthalmological follow up study of 2892 liquidators were. Results: Our findings showed that of neuropsychiatric pathology increased (Pv<0.001) in parallel with with radiation dose. Even cognitive impairment at doses >0.3 Sv was dose-dependent (r=0.4-0.7; P=0.03-0.003). Depression and neurocognitive deficit were more severe at higher doses (≥50 mSv). Disturbed brain information processes lateralized to the Wernicke's area were observed at doses >50 mSv. There is an increasing latency and decreasing of amplitude of cognitive visual potentials in liquidators, and eye vascular pathology as the most early and widespread radiation effect, namely retinal angiopathies and premature development of retinal angiosclerosis. Relative risk of retinal angiopathy morbidity is 1.65 (1.02; 2.67) at χ² = 4.15; p = 0.041. Conclusions: According to, our observations, IR represents a significant risk factor for the development of neurocognitivebehavioural disorders, that may be accompanied also by vascular ophtalmological disturbances, such as retinal angiopathias). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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