| Autor: |
Cheng, Qi, Li, Zhu, Wang, Xu, Wang, Shuo, Liu, Yijia, Huang, Mengnan, Li, Yue, Xue, Xiaoxue, Bu, Huaien, Yang, Rongrong, Xu, Yilan, Li, Lin, Gao, Shan, Zheng, Yanchao, Yu, Chunquan |
| Předmět: |
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| Zdroj: |
Angiology; Jan2023, Vol. 74 Issue 1, p39-46, 8p |
| Abstrakt: |
Remnant cholesterol (RC) and non-high-density lipoprotein cholesterol (non-HDL-C) are associated with coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM). However, the association between RC, non-HDL-C, and CHD patients with T2DM has not been comprehensively investigated. We analyzed the association between RC, non-HDL-C, and cardiac function in CHD patients with T2DM. Of the 22 022 CHD patients from six hospitals in Tianjin, 5373 (24.4%) patients with T2DM had higher levels of RC and non-HDL-C (P <.001) than those without T2DM. Among CHD patients with T2DM, RC and non-HDL-C were positively associated with New York Heart Association (NYHA) class Ⅱ [RC: odds ratio (OR), 1.74; 95% confidence interval (CI), 1.50–2.01; P <.01; non-HDL-C: OR, 1.23; 95% CI, 1.15–1.31; P <.01]. After adjusting for confounding factors, this association remained (RC: OR, 1.22; 95% CI, 1.03–1.45; P <.05; non-HDL-C: OR, 1.09; 95% CI, 1.02–1.17; P <.05). These findings provide evidence of an independent positive association between RC, non-HDL-C, and NYHA functional classes. More research is warranted to confirm these findings and determine the mechanisms involved. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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