Prozone phenomenon in secondary syphilis with HIV co-infection: Two cases.

Autor: Awake, Praneet, Angadi, Kalpana, Sen, Sourav, Bhadange, Prasad
Zdroj: Indian Journal of Sexually Transmitted Diseases & AIDS; Jul-Dec2022, Vol. 43 Issue 2, p183-185, 3p
Abstrakt: Prozone phenomenon is defined as a false-negative response resulting from higher antibody titer which interferes with formation of antigen–antibody lattice, necessary to visualize a positive flocculation test. The prozone effect can be observed in syphilis testing with cases of very high antibody titers, such as secondary syphilis, or with human immunodeficiency virus (HIV) co-infection. We report two cases of prozone phenomenon in secondary syphilis with HIV co-infection who initially tested nonreactive for rapid plasma reagin test but tested positive with further higher dilution. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index