| Autor: |
Poirier, Jackie Bibeau, Nguyen, Félix, Bélair, Manon, Moubayed, Sami P., Ayad, Tareck |
| Zdroj: |
Otolaryngology-Head & Neck Surgery; Aug2011 Supplement S1, Vol. 145, pP175-P175, 1p |
| Abstrakt: |
Objective: The value of laryngeal sclerosis as a sign of neoplastic invasion on CT‐scan is controversial. We investigated the value of laryngeal cartilage sclerosis on CT‐scan as a predictor of locoregional control, success of organ preservation, and survival for patients treated with radiation therapy for laryngeal carcinoma. Method: Retrospective chart review on patients treated for laryngeal carcinoma with radiation therapy at the CHUM between 2002 and 2007. A head and neck radiologist revised each patient's pretreatment CT‐scan to determine the presence of laryngeal cartilage sclerosis. This variable was correlated with locoregional control, laryngectomy, and survival rates. Results: Of the 111 patients, 76% were male and 24% female. Their mean age was 61 years. Forty‐eight had supraglottic tumors and 63 had glottic tumors. Seven percent had thyroid cartilage sclerosis, 5% cricoid cartilage sclerosis, 55% arytenoid cartilage sclerosis, and 16% arytenoid cartilage sclerosis with adjacent tumor. There was no significant correlation demonstrated between cartilage sclerosis and locoregional control rate, laryngectomy rate and global and disease‐free survival. Conclusion: Cartilage sclerosis on CT‐scan cannot be identified as a powerful predictor of treatment failure for patients with laryngeal carcinoma treated with radiation, which confirms our therapeutic attitude. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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