| Autor: |
R. J., Krishnasree, M., Ameena, P., Jayanthi, Rathy, R., T., Nripan |
| Předmět: |
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| Zdroj: |
Oral & Maxillofacial Pathology Journal; Jul-Dec2022, Vol. 13 Issue 2, p121-123, 3p |
| Abstrakt: |
Introduction: SARS-CoV-2 viral infection and the consequent COVID-19 disease rolled over the globe sweeping human lives and national health systems. Early diagnosis plays an important role in stopping its further escalation. Saliva as a Diagnostic Tool: Reverse transcription polymerase chain reaction (RT-PCR) remains the gold standard in the diagnosis of COVID-19 disease. Nasopharyngeal/oropharyngeal swabs are the recommended specimen types for identification of viral RNA. However, false negative results may occur due to inadequate or improper oropharyngeal sampling. Saliva, as a promising alternative, circumvents the limitations associated with the use of nasopharyngeal/oropharyngeal swabs and lessens the exposure risk of health care professionals. Salivaomics or salivary diagnostics includes the study of salivary proteins, salivary RNAs, salivary metabolites, salivary microRNAs and salivary microbiota. Saliva sample collection is easy, non-invasive and more acceptable for repeat testing and can be performed by non-healthcare professionals or even be self-sampled. Recent studies suggest that the sensitivity of saliva-based SARS-CoV-2 RNA detection methods seem to be comparable to or better than that of nasopharyngeal swabs. Conclusion: This paper reviews the role of saliva in the diagnosis of covid-19 infection, with special emphasis on its advantages, limitations and clinical implications. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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