| Autor: |
Kovalevsky, Ruslan A., Kucherenko, Alexander S., Zlotin, Sergei G. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 11/28/2022, Vol. 58 Issue 92, p12827-12830, 4p |
| Abstrakt: |
A bifunctional tertiary amine-squaramide-catalyzed enantioselective Mannich-type addition of available allomaltol to N-protected aldimines was developed. The resulted adducts were readily transformed into non-proteinogenic α-amino acids and their derivatives were not easily accessible by other methods via oxidative fragmentation, esterification, amidation and deprotection reactions. The absolute (S)-configuration of the thus obtained α-amino acids was established by comparison of the N-Ts-PheGly optical rotation sign with the reported data. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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