| Autor: |
Shami, Amber, Butt, Maleeha Tahir, Tahir, Saba, Chaudari, Zarrin Khaliq, Sajjad, Sajjad Ali, Shaherzadi, Marrium |
| Předmět: |
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| Zdroj: |
Professional Medical Journal; Nov2022, Vol. 29 Issue 11, p1672-1676, 5p |
| Abstrakt: |
Objectives: To determine hepatoprotective effects of cornsilk extracts through laboratory and histopathological parameters in albino rats. Study Design: Experimental Animal study. Setting: Animal House and Histology Laboratory of Postgraduate Medical Institute (PGMI) Lahore. Period: April 2019 to April 2020. Material & Methods: The study was carried out on 30 albino rats and was divided among three groups having ten rats in each group. Group A was labelled as a control group. Groups B and C were labelled as experimental groups. Cellular steatosis as a histological parameter and ALT and AST levels are measured to access the hepatoprotective effects of corn silk. Results: It was found that the mean AST and ALT were also significantly different among the groups analyzing p-value < 0.001. Fisher's exact test showed that there was significant difference in the percentage of cellular steatosis among groups. Conclusion: It was found that cornsilk extract can be recommended as a hepatoprotective agent against DOX-induced hepatic damage. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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