| Autor: |
Kusalkar, Minal J., Hatekar, Abhay D. |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 7, p288-295, 8p |
| Abstrakt: |
Introduction: The global prevalence of hypertension has increased to more than 25% of the world population, which is predicted to be increased to 65% by 2025. several studies have found that pediatric hypertensives have decreased heart rate variability (HRV) and higher sympathetic modulation/activation. Evidence suggests that this population may be predisposed to hypertension despite having high arterial blood pressure due to the likelihood of a genetic syndrome of abnormalities. This indicates that the development of hypertension in the children of hypertensives may be significantly influenced by cardiac autonomic dysfunction. Aims and Objectives: To evaluate the cardiac autonomic modulation in normotensive individuals of hypertensive parents compared to controls. Materials and Methods: This prospective study was conducted on 100 individuals, out of which 50 of them had a family history of hypertension and another 50 individuals without any family history of hypertension. Anthropometric measurements were taken along with weight, arterial blood pressure, and nerve conduction. Results: The study has found both systolic and diastolic pressure to be significant in the cold pressor test (p<0.05). It has also been shown that there is a significant difference between the two groups (p<0.05) in both the systolic and diastolic blood pressure, before and after Isometric Handgrip Test (IHGT). The study has found that heart rate variability is significantly different between the study and control group for each index (p<0.05). Conclusion: The study has found that the systolic and diastolic pressure is significantly higher in individuals with a family history of hypertension after performing the cold pressor test, isometric handgrip test and nerve conduction test (p<0.05). The study has shown that autonomic reactivity can be utilized to determine potential hypertension as a screening method for preventive diagnostics of hypertension. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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