Role of probiotics in surgical site infections at a tertiary care teaching hospital of border region of North India.

Autor: Talwar, Ashutosh, Kumar, Ashwani, Nagpal, Nitin, Chhabra, Ashish
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 7, p260-264, 5p
Abstrakt: The aim of the present study was to estimate the effect of the perioperative administration of probiotics in patients undergoing abdominal surgeries. The study focused on a total of 251 consecutive surgeries carried out from among all the elective surgeries performed between April 2021 and May 2022. The patients involved in surgeries undertaken between April 2021 and October 2021 were placed in the non-probiotic group (group A, 116 patients) and those involved in surgeries between November 2021 and May 2022 were placed in the probiotic group (group B, 135 patients). Postoperative infectious complications were recorded, and the immune responses and fecal microbiota were determined. A breakdown of infectious complications showed that 21 (8.36%) patients experienced superficial incisional surgical site infections, of which 16 patients were from group A (6.5%), and five patients from group B (1.99%). In conclusion, probiotic treatment can reduce superficial incisional surgical site infections in patients undergoing surgeries. Perioperative probiotic treatment can enhance immune responses and improve the intestinal microbial environment. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index