AMYLOIDOSIS IN CLINICAL PRACTICE: HOW TO DIAGNOSE.

Autor: Purwowiyoto, Sidhi Laksono, Kusharsamita, Hillary, Nurusshofa, Zahra, Mustifah, Etty Farida
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2022, Vol. 13 Issue 7, p1-15, 15p
Abstrakt: Amyloidosis is a rare disease in which insoluble amyloid proteins are deposited in the organs. Deposits cause tissue damage and organ dysfunction, especially in the heart, kidneys, and nerves. Cardiac amyloidosis (CA), particularly transthyretin (ATTR) and immunoglobulin light chains (AL) amyloidosis, has arisen as a frequently unrecognized cause of heart disease and death. Underdiagnosis was mainly due to a lack of recognition of the true prevalence and the non-specific signs of the disease. High clinical suspicion is required to promote early diagnosis. This article overviews various diagnostic tests for amyloidosis, emphasizing cardiac amyloidosis in innovative diagnostic methods. Furthermore, an algorithm of summary assessing the diagnosis of amyloidosis is presented. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index