NIOSOMES: AN EFFICIENT AND UNCONVENTIONAL METHOD OF DRUG DELIVERY.

Autor: Vyas, Deepak, Mukhopadhyay, Sayantan, Tamta, Bhupendra
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Zdroj: Biochemical & Cellular Archives; Oct2022, Vol. 22 Issue 2, p4273-4280, 8p
Abstrakt: Niosomes are nonionic surfactant vesicles that may be produced by the condensation of artificial nonionic surfactants with or without the addition of cholesterol or similar lipids. Niosomes are also known as niosomes. These are vesicular systems that are very similar to liposomes, and they have the potential to act as carriers for medications that are both amphiphilic and lipophilic. Niosomes are a viable vehicle for drug administration due to the fact that they are non-ionic. In addition, Niosomes are biodegradable, biocompatible, and non-immunogenic, and they demonstrate flexibility in their morphological characterization. In the treatment of cancer, viral infections, and other microbial disorders, niosomes have been the subject of extensive research and testing for controlled drug release and targeted drug delivery. Niosomes have the ability to ensnare hydrophilic as well as lipophilic medicines and once inside, they may extend the circulation of the substance that they have ensnared. It is hypothesized that encapsulating a medication in a vesicular system would let the drug last for a longer period of time in the systemic circulation, increase its penetration into the target tissue, and maybe lower its toxicity, provided that selective absorption can be accomplished. The benefits, disadvantages, production techniques, variables impacting, characterizations, invitro methodologies, release of drug kinetics, and implementations of noisome are the primary topics of discussion in this review paper. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index