IMMUNOLOPATHOGENESIS ROLE OF TOLL-LIKE RECEPTOR MARKERS (TLR2, TLR4 AND TLR9) IN PATIENT ASSOCIATED WITH TUBERCULOSIS IN BASRAH, IRAQ.

Autor: Mahdi, Kadhim Abbas, Alsaimary, Ihsan Edan
Předmět:
Zdroj: Biochemical & Cellular Archives; Apr2022, Vol. 22 Issue 1, p1235-1244, 10p
Abstrakt: A case control study has been carried among pateints with Tuberculosis, who attended to the Consultation Center of Chest and Respiratory diseases of Basrah province during 1st September 2020 to 1st June 2021. From total number of (176) patients with Tuberculosis (TB) were taken from Basrah province that included in the present study. The age of patients was between 14 - <80 years and (88) individuals regarded as control group without any pulmonary problems, the maximum number of tuberculosis patients was recorded for the age (20-29) years were 23 (26.1 %), followed by the age (30-39) years were 16 (18.2 %), while the age (40-49) years 14 (15.9%), closely with the age (10-19) years 13 (14.8%) and then the age (50-59) years 12 (13.6%), less number of cases for tuberculosis patients observed at the age (>60) years were 10 (11.4%) from total study cases. The immuonological study shown that the mean concentration of TLRs in TB patients as follows: the TLR2 was (0.65 ±0.27) (ng/ml), while in TLR4 was (3.19 ± 1.78) (ng\ml), and the TLR9 was (1.92 ± 1.06), the differences were highly-significant (P-value= 0.00). The levels of TLR2, TLR4 and TLR9 with age group (Yrs.) with (r = 0.07, 0.01, 0.14), respectively. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index