| Autor: |
Mohammed, Walaa Saeb Mejbel, AbdulZahra, Hind Abdulkadim, Edan, Ban Jabir |
| Předmět: |
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| Zdroj: |
Biochemical & Cellular Archives; Apr2022, Vol. 22 Issue 1, p673-677, 5p |
| Abstrakt: |
Intracytoplasmic sperm injection is an invasive technique using surgically retrieved testicular sperm could be associated with many complications. Researchers try to evaluate the role of the male sex hormones and the testicular size as a biomarker for success of such invasive procedure. The objectives is to evaluate the preoperative factor that can predict the outcome and success of testicular sperm retrieval. A retrospective cohort study included 319 infertile male with non-obstructive azoospermia underwent surgical sperm retrieval in AL-Najaf Fertility Centre. They were divided into two groups according to the result of testicular sperm retrieval procedure. Group one in whom the patient had sperm (TSR positive) and group two patient had no sperm (TSR negative) after the procedure. FSH, LH level is significantly higher in patients with negative outcome than corresponding group (23.88 ± 16.45) versus (16.70 ± 15.93), P value <0.001 (8.46 ± 6.09) versus (6.10 ± 5.51) P value <0.001, respectively. 75% of patients with negative outcome have FSH level more than normal reference value versus 57% in patients with positive outcome this is a significant statistical difference, P value = 0.01. Significantly higher percentage (33%) of patient with negative outcome have LH level more than normal reference range versus 8% in corresponding group. No significant difference in prolactin and testosterone hormone between both groups (11.35 ± 6.29) versus (12.41 ± 15.70) P value = 0.214, (372.99 ± 177.88) versus (396.87 ± 219.41) P value = 0.455. 15.1% of patients with negative TSR had smaller than average testes versus 16.5% in corresponding group, P value = 0.731. In conclusion, serum level of LH and FSH hormone may be used as a prognostic indicator of surgical sperm finding in patients with non-obstructive azoospermia. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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