Exploring People's Knowledge of Genetics and Attitude towards Genetic Testing: A Cross-Sectional Study in a Population with a High Prevalence of Consanguinity.
Autor: | Alotaibi, Amal, Alkhaldi, Njoud Khaled, AlNassir, Areej Mustafa, AlAyoubi, Leenah Ayman, AlMalki, Nada Abdulrahman, Almughyiri, Rahaf Abdullah, AlDosary, Reem Hussain, Cordero, Mary Anne Wong |
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Předmět: |
GENETICS
ANALYSIS of variance CROSS-sectional method MULTIVARIATE analysis GENETIC testing HEALTH literacy T-test (Statistics) GENETIC carriers HEALTH attitudes QUESTIONNAIRES DESCRIPTIVE statistics RESEARCH funding CONSANGUINITY STATISTICAL sampling DATA analysis software SOCIODEMOGRAPHIC factors PUBLIC opinion PRECONCEPTION care |
Zdroj: | Healthcare (2227-9032); Nov2022, Vol. 10 Issue 11, p2227, 14p |
Abstrakt: | This study investigated people's knowledge of genetics, attitudes toward genetic testing, and views on consanguinity. This cross-sectional study utilized a validated questionnaire modified from published studies to collect data on people's knowledge of genetics and attitudes about genetic testing among 1008 respondents from various Saudi Arabian regions. Using SPSS software version 26, data were analyzed using a t-test, ANOVA, and multivariate analysis. p-values of <0.05 were considered statistically significant. About 59.9% of the participants had sufficient knowledge of genetics, and around 50% had a favorable attitude toward genetic testing. Knowledge of genetics is significantly correlated (p ≤ 0.001) with a positive attitude toward genetic testing. Gender, age, level of education, marital status, family income, and family history were significantly correlated with respondents' understanding of genetics. Gender, family income, residence, and family history were associated with attitudes toward genetic testing at a 0.05 level of significance. There is a need to strengthen peoples' knowledge of genetics and attitudes toward genetic testing through diverse educational programs and healthcare strategies. Impetus on how to disseminate genetic information on consanguinity and transmission of diseases should be prioritized in regions where consanguineous marriages are high. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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