| Autor: |
Arduino, Paolo G., Gambino, Alessio, Giaccone, Luisa, Suria, Marco, Carbone, Mario, Carrozzo, Marco, Broccoletti, Roberto, Conrotto, Davide |
| Předmět: |
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| Zdroj: |
Special Care in Dentistry; Nov2022, Vol. 42 Issue 6, p585-591, 7p |
| Abstrakt: |
Aim: To describe oral cavity changes in patients who underwent a hematopoietic stem cell transplantation (HSCT). Methods and results: A group of 32 patients was studied after a mean period of 48.8 months (±11.22) from HSCT; oral, dental, and periodontal status were collected and compared with those of healthy matched controls. Unstimulated whole salivary flow (UWS) and salivary pH were also measured. A validated questionnaire (EORTC QLQH&N‐35) was used for reported quality of life. Fifty‐nine percent of patients were affected by chronic graft‐versus‐host disease (cGVHD). Dental health and periodontal status were statistically worse than in controls (P =.003 and P =.008, respectively). Regarding the HSCT group, UWS was statistically lower, and EORTC QLQH&N‐35 significantly higher than those reported in controls (P =.000 for both). There was no statistical correlation between hypo‐salivation and conditioning, presence of cGVHD, type of medication used before and after transplantation, and time of follow‐up. A reduction in salivary pH has been noted only for patients with erosive oral lesions. Conclusion: The oral cavity of HSCT patients appeared to undergo substantial modifications and the quality of life was deeply compromised. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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