| Autor: |
Ohkawa, S., Martin, L. N., Fukunishi, Yukiko, Gormus, B. J. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; Jan1987, Vol. 67 Issue 1, p43-50, 8p |
| Abstrakt: |
We investigated nine rhesus monkeys (Macaco mulatta) inoculated with Mycobacterium leprae and three normal human contacts. Peripheral blood monocytes were separated into Fc receptor positive (FcR + ) and Fc receptor negative (FcR-) fractions, and their regulatory role in the lymphoproliferative response in vitro to M. leprae was studied, FcR -- monocytes had strong antigen presentation activity and produced no suppressor effect while FcR+ monocytes had weak antigen presentation activity and produced a non-specific suppressor factor spontaneously. With this assay system we determined that M. leprae-inoculated rhesus monkeys could be divided into three groups: good responders. very weak responders. and non-responders. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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