| Autor: |
Yang, Yong-Cheng, Liu, Lu-Qi, Wang, Kun-Jun, Zhang, Xue-Qing, Fan, San-Peng, Gao, Xiao-Xu, Wang, An-Hua, Jia, Jing-Ming, Fu, Chun-Wang |
| Předmět: |
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| Zdroj: |
Natural Product Research; Nov2022, Vol. 36 Issue 21, p5429-5437, 9p |
| Abstrakt: |
Four sesquiterpenoids A-D (1–4) were isolated from the ethanol extracts of the leaves and stems from Schisandra chinensis. Their structures and absolute configurations were elucidated by a combination of NMR, MS and ECD. Compounds 1–4 (10 μM) exhibited moderate hepatoprotective activities against APAP-induced LO2 cell damage with increasing cell viability by 18%, 17%, 16%, and 19% compared to the model group (bicyclol, 26%) at 10 μM, respectively. All the compounds displayed no cytotoxic activity against five human cell lines, which also suggested the safety of leaves and stems of S. chinensis as an edible vegetable in a degree. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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