| Autor: |
Jones, A. Louise, Barth, Peter T., Wilkins, Brian M. |
| Předmět: |
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| Zdroj: |
Molecular Microbiology; Mar1992, Vol. 6 Issue 5, p605-613, 9p, 3 Diagrams, 5 Charts, 2 Graphs |
| Abstrakt: |
The Incl1 conjugative plasmid Collb-P9 carries a psiB gene that prevents induction of the SOS response in host bacteria. This locus is located 2.5 kb downstream of the ssb (single-stranded DNA-binding protein) gene in the leading region. This portion of Collb is strikingly similar to part of the leading region of the otherwise distinct F plasmid. Expression of psiB and ssb is increased when the host cell is exposed to an SOS-inducing treatment or the Collb transfer system is derepressed. Moreover, expression of both genes on a derepressed plasmid is strongly enhanced in conjugatively infected recipient cells. Carriage of the psiB gene by Collb is shown to prevent a low level of SOS induction following conjugation. Plasmid ssb and psiB genes may function to promote installation of the replicon in the new cell. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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