| Autor: |
Chhikara, Urvashi, Anand, Keerthana, Sharma, Akshatha, Prasad, Smriti, Kaul, Anita |
| Předmět: |
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| Zdroj: |
Journal of Ultrasound in Medicine; Nov2022, Vol. 41 Issue 11, p2877-2883, 7p |
| Abstrakt: |
Objectives: The objective of this study is to examine the performance of Ductus venosus (DV) Doppler done at the routine first trimester screening (11–13 + 6 weeks) in predicting the adverse fetal outcomes in Indian population. Methods: This observational study was conducted between 2013 and 2019, on 4340 singleton pregnancies. Ductus Doppler were considered abnormal if DV pulsatility index values were >95th centile for that gestation or with a reversed "a" wave. Anatomical survey was done to rule out other abnormalities. Women were followed up till delivery and outcomes were divided into 4 groups: 1) aneuploidies; 2) cardiac defects; 3) non‐cardiac structural abnormalities; and 4) miscarriages before 24 weeks or fetal deaths after 24 weeks. Results: Prevalence of abnormal DV Doppler is 5.12% (205/4004). There were significantly higher number of fetal losses (4.4 versus 0.3%), aneuploidies (10.2 versus 1.7%), fetal cardiac defects (5.9 versus 1.4%), and non‐cardiac structural defects (5.4 versus 1.4%) among the pregnancies with abnormal DV Doppler in comparison to those with normal flow (P <.001). Logistic regression analysis has shown that significant contribution to fetal chromosomal abnormalities and cardiac defects was associated with abnormal DV. Other factors which were found to have a significant association with adverse fetal outcome were increased nuchal translucency and increased body mass index (BMI). Conclusion: DV Doppler in first trimester can be used as a screening tool for cardiac defects and fetal deaths. Women with abnormal DV Dopplers should be offered fetal echocardiography at 18–22 weeks and third trimester growth scans with Dopplers. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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