| Autor: |
Sorkhi, Hadi, Mollalo, Abolfazl, Bijani, Ali, Mehravar, Saeed, Pournasrollah, Mohammad, Moharerpour, Sahar Sadr, Rostami, Ali, Sadr Moharerpour, Sahar |
| Předmět: |
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| Zdroj: |
Journal of Tropical Pediatrics; Oct2022, Vol. 68 Issue 5, p1-7, 7p |
| Abstrakt: |
Some evidence suggests toxoplasmosis as an etiology of nephrotic syndrome (NS) in children; however, no observational study evaluated this relationship. In a case-control study, we enrolled 35 children with NS and 37 healthy children. All participants were examined for anti-Toxoplasma immunoglobulin G and M (IgG and IgM) antibodies using enzyme-linked immunosorbent assay. We also systematically reviewed the literature to assess this relationship. Prevalence of anti-Toxoplasma IgG was 17.4% and 13.5% in cases and controls, respectively, indicating a non-significant association (adjusted odds ratio, 1.22, 95% confidence interval, 0.35-4.41). No subjects were seropositive for IgM. In a systematic review, we found that acute toxoplasmosis can induce NS in some children and anti-Toxoplasma treatment is effective in the remission of NS in these cases. In pediatrics with NS, acute toxoplasmosis should be considered as a neglected causative factor. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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