Abstrakt: |
This article presents information regarding chemotherapy and superinfection in murine tuberculosis. listeriosis and salmonellosis. In the majority of bacterial infections, phagocytosis, with or without the assistance of specific antibody, is usually followed by the death and dissolution of the organisms. In others, however, represented by tuberculosis, brucellosis, listeriosis and salmonellosis, not only is the phagocytic macrophage the immediate target of infection, but, once inside the cell, the bacteria at first multiply freely and later persist in this situation despite the intervention of a bactericidal phase of immunity. |