| Autor: |
Row, A.E., McEwancowan, B., Eddleston, A.L.W.F., Thompson, A.D. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; Aug1981, Vol. 45 Issue 2, p305-307, 3p |
| Abstrakt: |
An attempt was made to produce a model of autoimmune hepatitis in AKR mice by immunization with allogeneic liver extract or a purified (human) liver-specific lipoprotein (LSP). Although a mononuclear infiltrate was found in the liver in recipients of purified liver antigen and to a lesser degree in recipients of allogeneic extract, this was associated with the development of an acute thymus-derived leukaemia. This mouse strain is normally susceptible to leukaemia after a latent period of approximately 6 to 9 months hut the immunization schedule markedly reduced the age of onset of this disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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