| Abstrakt: |
Introduction: Diffuse large B-cell lymphoma is the most common histological subtype of non-Hodgkin lymphoma, with a male predominance (55%). In only 40% of cases, the disease arises in extranodal tissues, the gastrointestinal system being the most common site. However, it can occur in any lymphoid tissue. Objective: To report a case of diffuse primary large B-cell lymphoma of the laryngotracheal system. Case report: Male patient, 57 years old, complaining of progressive weight loss, 15 kilograms in 5 months, associated with cervical edema, dysphagia for solids, dysphonia and dyspnea on minor exertion, air gap of 5%. An emergency tracheostomy was performed, with laryngeal biopsy performed concomitantly. The anatomopathological examination confirmed the diagnosis of poorly differentiated malignant neoplasm with a pattern of small round and blue cells. Material sent for immunohistochemistry that confirmed diffuse large B-cell lymphoma, with positive for CD 20, CD 10 and BCL6 protein. Conclusion: Although rare, laryngotracheal symptoms can be present and even be the main findings of a diffuse B-cell lymphoma and should always be investigated. [ABSTRACT FROM AUTHOR] |
