10-year-old mucocutaneous leishmaniasis: extensive involvement with severe consequences.

Autor: Alves Marroni, Gabriela, Hamerschmidt, Rogerio, de Oliveira Luciani, Guilherme, Duarte Costa Barth Costamilan, Anne Louise Tortato, Yumi Nakagawa, Érika, Polo Silveira, Luísa, Ferreira Iunklaus, Louise
Předmět:
Zdroj: International Archives of Otorhinolaryngology; 2022 Supplement, Vol. 26, p35-36, 2p
Abstrakt: Introduction: Leishmaniasis is a disease caused by the protozoa of the Leishmania genus and transmitted by phlebotomine insects. Although it is classically presented as an ulcer on the skin, mucosal lesions can also occur. The nasal mucosa is the main area affected, but pharynx and larynx may also be involved. Objectives: To report a case of mucocutaneous leishmaniasis with nasal and laryngeal involvement, with more than 10 years of evolution, addressing its diagnostic difficulty. Resumed report: 57-year-old male, farmer, admitted to a tertiary service with dysphonia and dysphagia for more than10 years, associated with ulcerated and infiltrative lesions in the nasal vestibule and infranasal region with involvement of the palate. He had already been submitted to previous treatments with misdiagnoses, without improving the condition. Nasofibrolaryngoscopy revealed a granulomatous lesion affecting the nasal mucosa, oropharynx and the larynx, in addition to significant circumferential edema and narrowing of the glottic cleft. Tracheostomy was chosen to protect the airway and the patient was submitted to suspension laryngoscopy with biopsy of the injury, whose histopathological results showed linfohistioplasmocitary inflammation and presence of Leishman-Donovan bodies. Treatment with liposomal amphotericin B was initiated, with clinical improvement of the condition, and the patient is being followed up with the Infectology team of our service. Conclusion: This case reports the serious consequences that misdiagnose may present. Leishmaniasis should be treated as a differential diagnosis in several infectious conditions, and early and adequate diagnosis is essential to avoid deformities and functional complications. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index