| Autor: |
Oliveira Correia, Luisa, Costa Oliveira, Patricia, Medeiros Dias Lopes, Natália, Aurelio Fornazieri, Marco |
| Předmět: |
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| Zdroj: |
International Archives of Otorhinolaryngology; 2022 Supplement, Vol. 26, p2-2, 1/4p |
| Abstrakt: |
Introduction: Photobiomodulation therapy is a non-invasive treatment that uses photons of light from the red to infrared spectrum to modulate cellular processes. Works as an anti-inflammatory and regenerating properties, and its application in the health area has been growing. With the COVID-19 pandemic, an increasing number of patients have presented olfactory disorders, possibly due to the interaction of SARSCoV-2 in the olfactory epithelium, triggering the inflammatory process. Objective: To evaluate a possible effective treatment for olfactory alterations, this study aimed to analyze the use of intranasally applied photo bio modulation therapy in patients with olfactory dysfunction after COVID-19. Methods: This study is a randomized, placebo-controlled clinical trial with 59 patients with persistent olfactory disorders after SARS-CoV-2 infection, which were subdivided into 3 groups randomly: placebo group (n=19), red light group (n=22) and infrared light group (n=18). Ten laser application sessions were established with 4J in each narin for 40 seconds. All groups used systemic corticosteroids for 5 days and olfactory training for 90 days. Olfactory function was assessed by the University of Pennsylvania Smell Identification Test. Results: Patients in the red light (21.0 ± 6.6 vs 24.2 ± 6.5 p<0.01) and infrared light (22.0 ± 7.3 vs 28.2 ± 4.3, p<0.01) groups obtained a statistically significant improvement in olfactory function. Results were not observed in the placebo group (19.5 ± 7.0 vs 21.5 ±5.6, p=0.06). Conclusion: Photobiomodulation therapy may play an important role in the recovery of post-COVID olfactory disorders and represents a promising treatment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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