Autor: |
Binwei Lin, Dan Huang, Feng Gao, Yiwei Yang, Dai Wu, Yu Zhang, Gang Feng, Tangzhi Dai, Xiaobo Du |
Předmět: |
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Zdroj: |
Frontiers in Oncology; 9/23/2022, Vol. 12, p1-8, 8p |
Abstrakt: |
FLASH radiotherapy (FLASH-RT) is a novel radiotherapy technology defined as ultra-high dose rate (= 40 Gy/s) radiotherapy. The biological effects of FLASHRT include two aspects: first, compared with conventional dose rate radiotherapy, FLASH-RT can reduce radiation-induced damage in healthy tissue, and second, FLASH-RT can retain antitumor effectiveness. Current research shows that mechanisms of the biological effects of FLASH-RT are related to oxygen. However, due to the short time of FLASH-RT, evidences related to the mechanisms are indirect, and the exact mechanisms of the biological effects of FLASH-RT are not completely clear and some are even contradictory. This review focuses on the mechanisms of the biological effects of FLASH-RT and proposes future research directions. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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