The Pragmatic Role of COVID-19 on the Thrombus Grade of Patients with Contemporary ST-Segment-Elevation Myocardial Infarction.

Autor:	Firouzi, Ata, Hosseini, Zahra, Norouzi, Zeinab, Hosseini, Zohre, Amirpour, Afshin, Talakoob, Hamed, Amin, Arash, Soleimani, Abbas, Moradifar, Nasrolah, Karbalai, Shahrokh, Mozafarybazargani, Mohammadhossein, Hekmat, Hamidreza, Maleki, Majid, Sadeghipour, Parham, Mirbod, Seyedeh Mahnaz, Kohnaki, Mina Ghorbanpoor, Bakhshandeh, Hooman, Nia, Masoomeh Kalaei, Habibizade, Fatemeh Sadate, Iraninejad, Sara
Předmět:	CARDIOVASCULAR disease related mortality RESEARCH COVID-19 PERCUTANEOUS coronary intervention CEREBROVASCULAR disease STROKE CORONARY artery stenosis CORONARY artery bypass MAJOR adverse cardiovascular events RETROSPECTIVE studies CASE-control method ST elevation myocardial infarction CORONARY thrombosis TREATMENT effectiveness DESCRIPTIVE statistics DISEASE complications EVALUATION
Zdroj:	Journal of Tehran University Heart Center; 2022, Vol. 17 Issue 3, p103-111, 9p
Abstrakt:	Background: Limited data exist on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) presenting with ST-segment-elevation myocardial infarction (STEMI). Methods: This multicenter study, conducted in 6 centers in Iran, aimed to compare baseline clinical and procedural data between a case group, comprising STEMI patients with COVID-19, and a control group, comprising STEMI patients before the COVID-19 pandemic, and to determine in-hospital infarct-related artery thrombus grades and major adverse cardiocerebrovascular events (MACCEs), defined as a composite of deaths from any cause (cardiovascular and noncardiovascular), nonfatal strokes, and stent thrombosis. Results: No significant differences were observed between the 2 groups regarding baseline characteristics. Primary percutaneous coronary intervention (PPCI) was performed in 72.9% of the cases and 98.5% of the controls (P=0.043), and primary coronary artery bypass grafting was performed in 6.2% of the cases and 1.4% of the controls (P=0.048). Successful PPCI procedures (final TIMI flow grade III) were significantly fewer in the case group (66.5% vs 93.5%; P=0.001). The baseline thrombus grade before wire crossing was not statistically significantly different between the 2 groups. The summation of thrombus grades IV and V was 75% in the case group and 82% in the control group (P=0.432). The rate of MACCEs was 14.5% and 2.1% in the case and control groups, respectively (P=0.002). Conclusion: In our study, the thrombus grade had no significant differences between the case and control groups; however, the in-hospital rates of the no-reflow phenomenon, periprocedural MI, mechanical complications, and MACCEs were statistically significantly higher in the case group. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu