Comparison of Stool Antigen Test with Histopathology of Endoscopic Gastric Biopsies for Detection for Helicobacter Pylori; A Hospital-Based Study.

Autor: Zubair, Muhammad, Nawaid, Muhammad Amir, Afridi, Nabeel Khan, Baig, Bilal, Hanif, Muhammad, Mahmoud, Tamer Mohamed, Gabalunos, Helman Sansaet
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Zdroj: Pakistan Armed Forces Medical Journal; 2022 Supplement, Vol. 72, pS268-S268, 1p
Abstrakt: Objective: To evaluate the diagnostic accuracy of the H. pylori Stool Antigen (HPSA) test keeping histopathology as the gold standard. Study Design: Retrospective longitudinal study. Place and Duration of Study: Najran Armed Forces Hospital, Kingdom of Saudi Arabia, from Jan 2015 to Mar 2020. Methodology: A Total of 151 patients in whom H. pylori Stool Antigen test was done were included in the study. They were followed for their results of histopathology on gastric biopsies. Results: Among 151 patients 85 (56.3%) were females and 66 (43.7%) were males. The mean age was 40 ± 13.7 years. Fortythree (28.5%) patients were positive for both H. pylori Stool Antigen test and histology; fifteen (9.9%) patients were positive on the H. pylori Stool Antigen test but negative on histology. Twenty-two (14.6%) patients were negative on H. pylori Stool Antigen test but they were positive on histology. Seventy-one (47%) patients were negative for both H. pylori Stool Antigen test and histology. The sensitivity and specificity were 66.1% and 82.5%, respectively. Positive predictive value (PPV) was 74.1% and negative predictive value (NPV) was 76.3% for H. pylori Stool Antigen test. The diagnostic accuracy for this test was 75.5%. Conclusion: Keeping in view the low sensitivity and diagnostic accuracy H. pylori Stool Antigen test cannot be used as a screening tool in all patients; however it can be used for clinical correlation in setups where other diagnostic tests are not available due to the simplicity of its use, low cost and easy repeatability. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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