The neutrophil-to-lymphocyte ratio as a prognostic index for short-term outcome in the ICU admitted COVID-19 adult patients: a prospective cohort study.

Autor: Kamel, Emad Zarief, Sayed, Jehan Ahmed, Hashem, Maiada K., Elagan, Moataz, Soliman, Omar M.
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Zdroj: Research & Opinion in Anesthesia & Intensive Care; Jul-Sep2022, Vol. 9 Issue 3, p190-195, 6p
Abstrakt: Context The neutrophil-to-lymphocyte ratio (NLR), which can be easily computed from a standard blood test, has been found to be useful in determining a patient's overall inflammatory condition. Aim To find out if the NLR cut-off point could be used to predict mortality in coronavirus disease 2019 (COVID-19) patients admitted to the intensive care unit (ICU). Setting and design A prospective cohort study, carried out between March and August 2021, and included 92 COVID-19 ICU admitted patients of Assiut University Hospital. Methods and material The NLR, platelet-to-lymphocyte ratio (PLR), ventilation assessment, and shortterm outcome were assessed throughout the study period. Results Receiver operating characteristic curves analysis on the 7th day was done for NLR and PLR in relation to mortality rate. There was a high AUC for both NLR and PLR (0.946 and 0.931, respectively). The cut-off points were NLR 6.9 and PLR 258.35; above these, the mortality was increased. Patients who were discharged to home were 62 (67.39%), those who were transferred to an intermediate care unit were 9 (9.78%), and those who died were 21 (22.8%). Conclusion NLR and PLR levels above a certain threshold were linked to severe COVID-19 and mortality. Prior to clinical application, more research is needed to determine the best cut-off value for NLR. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index