Methotrexate induced pneumonitis – A case report and review of literature.

Autor: Vinay, V, Munjal, Sushil, Verma, Paras, Jain, Sandeep, Yadav, B, Sharma, Amit
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Zdroj: Journal of Family Medicine & Primary Care; Aug2022, Vol. 11 Issue 8, p4844-4846, 3p
Abstrakt: Methotrexate (MTX) is the commonly preferred drug in the treatment of various chronic inflammatory conditions. An uncommon, life-threatening, and fatal event associated with methotrexate use is methotrexate-induced pneumonitis (M-pneu). M-pneu does not correlate with the dosage, duration, or method of administration. We present a case of M-pneu in a diagnosed rheumatoid arthritis patient after six years of initiation of MTX. Prompt recognition, withdrawal, and supportive therapy have a positive outcome. If untreated, M-pneu has a proven fatality of 17–30% in published cases. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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