| Autor: |
Moukal, Abdellah, El Farouqi, Abdallah, Aghrouch, Mohamed, Chadli, Smail, Zekhnini, Abderrahmane, Izaabel, El Hassan |
| Předmět: |
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| Zdroj: |
Mediterranean Journal of Nutrition & Metabolism; 2022, Vol. 15 Issue 3, p361-368, 8p |
| Abstrakt: |
OBJECTIVES: Assessing Vitamin-D status and checking if low serum 25(OH)D is a factor in breast cancer (BC) for Southern Moroccan women. MATERIALS/METHODS: Study conducted in Morocco about women with BC (n = 90) and controls (n = 90). 25-hydroxy-vitamin-D biological analyzes executed during the first consultation. Social data and anthropometric parameters were collected for all participants. RESULTS: Women from urban areas constitued 67.78 % for the cases and 85.6% for the controls. The average age was 48.72±9.71 (cases) and 46.40±12.52 (controls). We found that 53.33% of cases and 40% of controls were postmenopausal and that hypovitaminosis-D affected 80 and 64.4% of cases and controls, respectively. Statistical analysis showed that hypovitaminosis-D was a significative risk factor for BC in Southern Moroccan women. The Odds Ratio was of 5 (p < 0.0001). The BC subtypes had Odds Ratios greater than 1. The highest value was obtained with Luminal B subtype (Odds ratio = 6.25; p = 0.0007). CONCLUSION: This study reinforces the evidence implicating hypovitaminosis-D among modifiable risk factors for BC. Further studies are needed to assess the extent of hypovitaminosis-D in Moroccan women with BC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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