| Autor: |
de Scheerder, I., Vandekerckhove, J., de Schrijver, G., Hoste, M., Clement, D., Wieme, R., Pannier, R. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; May1985, Vol. 60 Issue 2, p403-406, 4p |
| Abstrakt: |
Sera from 196 patients were collected before and after cardiac surgery to measure antibodies against heart tissue and against actin and myosin. In the post-operative period antibodies were found in 87 patients (44%) producing a cross-striated fluorescence pattern in heart tissue. Antibodies against the major contractile proteins were found in 91 patients (46%), anti-actin antibodies in 49 patients (25%) and anti-myosin antibodies in 65 patients (33%). We found a significant correlation (P < 0.0001) between the antibodies producing a cross-striated fluorescence pattern and antibodies recognizing contractile proteins. These results suggest that contractile proteins evoke an immune response after cardiac surgery and that this response may compromise cardiac function. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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