| Autor: |
Berrih, Sonia, Gaud, C., Bach, Marie-Anne, Brigand, H. Le, Binet, J. P., Bach, J. F. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Immunology; Jul1981, Vol. 45 Issue 1, p1-8, 8p |
| Abstrakt: |
Functional T cell subsets have been evaluated in the peripheral blood of patients with myasthenia gravis using monoclonal anti-T cell antibodies and a suppressor cell assay based on the suppression of the mixed-lymphocyte reaction by concanavalin A-activated lymphocytes. A significant decline of suppressor cells was found in a large proportion of patients, both by direct count using the anti-suppressor-cytotoxic T cell antibody (OKTS) and by the suppressor assay. Patients also showed an increase in immature T cells defined by their simultaneous reaction with the anti-helper cell (OKT4) and anti-suppressor cell (OKT8) antibody. Thymectomy tended to enhance the deficit in suppressor cells, and to induce the disappearance of double-labelled cells [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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