Colchicine in coronary artery disease.

Autor: Katira, Arnav, Katira, Ravish
Předmět:
Zdroj: Postgraduate Medical Journal; Sep2022, Vol. 98 Issue 1163, p718-721, 4p
Abstrakt: Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Inflammation has been seen to be a key feature of atherosclerosis and CAD, with a raised C-reactive protein being a marker of poor prognosis. Thus, the role of anti-inflammatory agents has been investigated in CAD. Colchicine is a well-known, inexpensive drug with marked anti-inflammatory effects. Here, we discuss the role of colchicine in stable CAD and post-acute coronary syndrome. We suggest that colchicine may play a key role in prevention of cardiovascular events in patients with stable and unstable CAD as colchicine is associated with a reduction in the rate of myocardial infarction and other major cardiovascular outcomes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index