Incidence of Malignancies Among Patients With Chronic Hepatitis B in US Health Care Organizations, 2006-2018.

Autor: Spradling, Philip R, Xing, Jian, Zhong, Yuna, Rupp, Loralee B, Moorman, Anne C, Lu, Mei, Teshale, Eyasu H, Schmidt, Mark A, Daida, Yihe G, Boscarino, Joseph A, Gordon, Stuart C
Předmět:
Zdroj: Journal of Infectious Diseases; Sep2022, Vol. 226 Issue 5, p896-900, 5p
Abstrakt: Hepatitis B virus (HBV) infection causes hepatocellular carcinoma but its association with other cancers is not well established. We compared age-adjusted incidence of primary cancers among 5773 HBV-infected persons with US cancer registries during 2006-2018. Compared with the US population, substantially higher incidence among HBV-infected persons was observed for hepatocellular carcinoma (standardized rate ratio [SRR], 30.79), gastric (SRR, 7.95), neuroendocrine (SRR, 5.88), cholangiocarcinoma (SRR, 4.62), and ovarian (SRR, 3.72) cancers, and non-Hodgkin lymphoma (SRR, 2.52). Clinicians should be aware of a heightened potential for certain nonhepatic malignancies among hepatitis B patients, as earlier diagnosis favors improved survival. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index