Biotransformation novel advances – 2021 year in review.

Autor:	Khojasteh, S. Cyrus, Argikar, Upendra A., Cho, Sungjoon, Crouch, Rachel, Heck, Carley J. S., Johnson, Kevin M., Kalgutkar, Amit S., King, Lloyd, Maw, Hlaing, Seneviratne, Herana Kamal, Wang, Shuai, Wei, Cong, Zhang, Donglu, Jackson, Klarissa D., Kramlinger, Valerie M., Dalvie, Deepak, O'Neill, James, Su, Dian, Teitelbaum, Aaron M., Totah, Rheem A.
Předmět:	BIOCONVERSION DRUG discovery MOLECULAR structure DRUG development
Zdroj:	Drug Metabolism Reviews; Aug2022, Vol. 54 Issue 3, p207-245, 39p
Abstrakt:	Biotransformation field is constantly evolving with new molecular structures and discoveries of metabolic pathways that impact efficacy and safety. Recent review by Kramlinger et al. (2022) nicely captures the future (and the past) of highly impactful science of biotransformation (see the first article). Based on the selected articles, this review was categorized into three sections: (1) new modalities biotransformation, (2) drug discovery biotransformation, and (3) drug development biotransformation (Table 1). [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.