| Autor: |
İbrahim, Ahmed Hassan, Güler, Emrah, Bağkur, Cemile, Süer, Kaya, Çelik, Eşref |
| Předmět: |
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| Zdroj: |
Journal of Academic Research in Medicine; 2022, Vol. 12 Issue 2, p55-60, 6p |
| Abstrakt: |
Objective: Staphylococcus aureus (S. aureus), including methicillin resistant S. aureus (MRSA), can produce biofilm leading to increased morbidity and mortality in hospital infections. Antibiotic resistance is an inherent feature of bacterial biofilms, and the formation of biofilms is more widespread in MRSA. This study aimed to reveal the phenotypic biofilm-forming abilities of S. aureus isolates and to investigate the relationship of antibiotic resistance of biofilm-forming S. aureus with biofilm formation. Methods: A cross-sectional descriptive study was carried out in the microbiology laboratory at the Near East University Hospital in the Turkish Republic of Northern Cyprus. A total of 67 non-duplicative samples (wound/pus, sputum, aspirate, blood and urine) for the study were collected between January 2020 and April 2021 from samples of inpatients and outpatients from various hospital departments. VITEK 2 system was used for bacterial identification and antibiotic susceptibility testing, biofilm formation was evaluated using Congo red agar (CRA). Results: It was observed that 56 (84.3%) of 67 S. aureus isolates cultured on CRA produced biofilm, while the remaining 11 (15.7%) were not biofilm producers. A statistically significant relationship was found between methicillin resistance and biofilm formation in S. aureus isolates. Accordingly, a significantly higher biofilm formation was observed in MRSAs compared to those with negative methicillin resistance (92.1% vs. 72.4%, p=0.034). A high proportion of isolates of S. aureus showed susceptibility towards tigecycline (100%) and gentamycin (100%). Conclusion: The findings of this study indicated that methicillin-resistant strains produced more biofilms and exhibited a high degree of resistance to most antibiotics. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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