Fabrication and characterization of composite PMMA/HA scaffold using freeze casting method.

Autor: Singh, Gurdev, Santhanakrishnan, Soundarapandian
Předmět:
Zdroj: Materials Technology; Sep2022, Vol. 37 Issue 11, p1734-1741, 8p
Abstrakt: A bone implant is one of the important areas in biomedical applications where biomaterial like polymers, ceramics and metals plays a deciding role. Polymethyl(methacrylate) (PMMA) is one of the biocompatible materials that can be used for fabricating bone implants. In this work, the combinations of PMMA, PMMA/HA, PMMA/Mg and PMMA/HA/Mg scaffolds were fabricated by the freeze casting process. The variation of pore size, porosity and compressive strength was studied for PMMA and its combinations with HA and Mg. The pore size in all four combinations was greater than 200 µm. This indicates that all four types of scaffolds are suitable for bone implants in their biological functions. The compressive strength of the PMMA/HA (26.08 MPa) scaffold was higher than the cancellous bone. In this work, PMMA/HA scaffold with better pore size and compressive strength was fabricated which has given way to fabricate bone implants in the near future. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index