| Autor: |
Filatova, S. M., Budanova, U. A., Sebyakin, Yu. L. |
| Zdroj: |
Moscow University Chemistry Bulletin; Oct2022, Vol. 77 Issue 5, p262-268, 7p |
| Abstrakt: |
In this paper, we describe the synthesis of cationic amphiphiles based on aliphatic and aromatic amino acids and diethanolamine derivatives. The calculation of the hydrophilic-lipophilic balance for a number of structures makes it possible to identify the structures with potential antimicrobial activity against gram-positive and gram-negative bacterial strains. The schemes for the synthesis of mono/bivalent cationic lipoamino acids and lipopeptides are developed. Two series of amphiphiles are obtained in preparative quantities for subsequent microbiological studies and determining the minimum inhibitory concentration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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