| Autor: |
Delyagina, E. S., Agafonov, M. A., Garibyan, A. A., Terekhova, I. V. |
| Zdroj: |
Russian Journal of Physical Chemistry; Aug2022, Vol. 96 Issue 8, p1687-1692, 6p |
| Abstrakt: |
A metal-organic framework based on γ-cyclodextrin and K+ cations synthesized by antisolvent vapor diffusion method is proposed as a delivery system for niflumic acid, a non-steroidal anti-inflammatory agent with limited aqueous solubility. Methods of loading niflumic acid into the framework are discussed. The resulting composites are characterized via XRD, low-temperature nitrogen sorption/desorption, and IR spectroscopy. Encapsulation in a metal–organic framework has effect on the kinetics of niflumic acid release and its membrane permeability. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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