| Autor: |
Li, Yeli, Feng, Linying, Xie, Dianyou, Lin, Mu, Li, Yiqi, Chen, Nana, Yang, Danli, Gao, Jianmei, Zhu, Yizhun, Gong, Qihai |
| Předmět: |
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| Zdroj: |
Antioxidants; Aug2022, Vol. 11 Issue 8, pN.PAG-N.PAG, 18p |
| Abstrakt: |
Effect of ICS II on SIRT3-KO Mice To further verify if loss of functional SIRT3 offsets ICS II preconditioning-induced cardioprotection in MI, WT and SIRT3-KO mice were treated with or without ICS II for 7 days prior to MI. ICS II Mitigated MI-Induced Myocardial Injury in Mice The left anterior descending coronary artery ligation-induced MI mice model was used to determine the effect of ICS II on MI-induced myocardial injury. Icariside II, a Naturally Occurring SIRT3 Agonist, Protects against Myocardial Infarction through the AMPK/PGC-1 /Apoptosis Signaling Pathway ICS II Inhibited Myocardial Apoptosis in Mice after MI We next investigated the role of apoptosis in the inhibitory effect of ICS II on MI. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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