| Autor: |
Paddick, Ian, Grishchuk, Diana, Karanatsiou, Anna |
| Předmět: |
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| Zdroj: |
Journal of Radiosurgery & SBRT; 2022 Supplement, Vol. 8, p116-117, 2p |
| Abstrakt: |
Introduction: Lightning is a novel optimizer based on a linear programming solution for Gamma Knife treatment planning. We wanted to compare planning results between manual plans created by expert users, a competing commercial optimiser (IntuitivePlan) and Lightning for a series of arteriovenous malformations (AVMs). Methods and materials: 20 consecutively treated AVM patients were selected and their manually created clinical treatment plans were used as the basis of this study. Replanning was performed using IntuitivePlan1 and Lightning. Lightning plans were optimised by varying low dose/beam on time weighting. Plan quality indices including coverage, selectivity, Paddick conformity index (PCI). Gradient Index (GI) and Efficiency Indices (EI) were compared and analysed to determine if a superior method of planning existed. Planning, beam on times and the number of isocentres were also noted. The difference in each parameter between one method over another was determined by a two-tailed t-test and was considered significant for p-values of <0.05. Results: Planning time was significantly lower when using the Lightning optimizer than other techniques, 1.0 vs 11.6 min, P<10-6 (Lightning vs Manual) and 1.0 vs 3.8 min, P<10-6 (Lightning vs IP). Lightning plans had higher Selectivity, PCI and lower GI than manual plans but these differences were not statistically significant. Conclusion: Lightning can produce high quality plans for AVMs in a significantly shorter time and in some cases the quality metrics are better compared to manual plans created by expert planners. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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