SYNTHESIS AND IN VITRO CYTOTOXIC EVALUATION OF NOVEL TRIAZOLE-BENZIMIDAZOLE EMBODIED PYRAZOLE DERIVATIVES AGAINST BREAST CANCER.

Autor: Dhoddi, Bala Narsimha, Kurapati, Ravi, Kundur, Govardhan Reddy, Bitla, Sampath, Puligilla, Balaswamy, Pochampally, Jalapathi
Předmět:
Zdroj: Rasayan Journal of Chemistry; Apr-Jun2022, Vol. 15 Issue 2, p1345-1351, 7p
Abstrakt: A new series of novel triazole -- benzimidazole containing pyrazole derivatives (10a-m) have been designed, synthesized, and characterized by their spectral data. These newly synthesized compounds (10a-m) were tested for their in vitro cytotoxic activity against MCF-7 human breast cancer cell lines. This shows that compound 10b proved to be the most prominent cytotoxic agent against MCF-7 cell lines. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index