Control Parameters for Separation and Concentration of Rat Erythrocytes and Lymphocytes and Human Erythrocytes in the Field of a Standing Ultrasonic Wave.

Autor: Pashovkin, T. N., Sadikova, D. G.
Zdroj: Biophysics; Jun2022, Vol. 67 Issue 3, p445-450, 6p
Abstrakt: The parameters of controlling the separation of erythrocyte and lymphocyte cells were studied; the possibility of rapid (minutes) separation of blood cells into fractions in the field of a standing ultrasound wave was shown. Seven main control parameters were identified; they were related to the energy of the field of the standing ultrasonic wave, the linear pumping rate of the cell suspension, the geometric dimensions of the cells, the ratio of cell densities and suspending media, and the ratio of ultrasound velocities in the cell material and suspending media. It was shown that under effective temperature control of the chambers of the ultrasonic separation and concentration systems with a suspension of cells, it is possible to significantly (by more than an order of magnitude) reduce the time of separation and concentration of cells not only of different types, but also of similarly-sized cells of the same type isolated from the blood of different animal species. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index