Effectiveness of aerobic and resistance training on the motor symptoms in Parkinson's disease: Systematic review and network meta-analysis.

Autor:	Xiao Zhou, Peng Zhao, Xuanhui Guo, Jialin Wang, Ruirui Wang
Předmět:	PARKINSON'S disease diagnosis RESISTANCE training EXERCISE tests ONLINE information services PSYCHOLOGY information storage & retrieval systems MEDICAL databases AEROBIC exercises META-analysis CONFIDENCE intervals MEDICAL information storage & retrieval systems SYSTEMATIC reviews OXYGEN consumption QUALITY of life SEARCH engines RESEARCH funding ALTERNATIVE medicine MEDLINE MOTOR ability EXERCISE therapy PROBABILITY theory
Zdroj:	Frontiers in Aging Neuroscience; 8/1/2022, Vol. 14, p01-21, 21p
Abstrakt:	Background/objectives: Aerobic and resistance training are common complementary therapies to improve motor symptoms in people with Parkinson's disease (PD), and there is still a lack of advice on which intensity and period of aerobic or resistance training is more appropriate for people with PD. Therefore, a network meta-analysis was conducted to assess the comparative efficacy of aerobic and resistance training of di erent intensities and cycles on motor symptoms in patients with Parkinson's disease. Methods: Based on several biomedical databases, a search strategy system was conducted to retrieve randomized controlled trials (RCTs) without language restrictions. A network meta-analysis with a frequentist approach was conducted to estimate the efficacy and probability rankings of aerobic and resistance training on Parkinson's patients. What's more, a range of analyses and assessments, such as routinemeta-analyses and risk of bias, were performed as well. Results: Twenty trials with 719 patients evaluating 18 di erent therapies were identified. Through the Unified Parkinson's DiseaseMotor Rating Scale, (UPDRS III); 6-minutewalk test, (6MWT); 10-meterwalk test, (TWM); and time up and go (TUG) and Quality of Life Scale-39 (PDQ-39), to explore the effects of di erent intensity resistance and aerobic exercise on PD. As a result, short period high intensity resistance movement (standard mean di erence (SMD) = -0.95, 95% confidence interval (CI) -1.68 to -0.22) had significantly decreased the Unified Parkinson's Disease Motor Rating Scale (UPDRS III). Short period high intensity resistance exercise showed similar superiority in other indices; also, aerobic and resistance training of di erent cycle intensities produced some efficacy in PD patients, both in direct and indirect comparisons. Conclusion: For patients with moderate to mild Parkinson's symptoms, short periods high intensity resistance training may provide complementary therapy for PD, and aerobic or resistance training of varying intensity and periodicity may be recommended as exercise prescription for PD patients. However, more large scale and high quality clinical trials are needed to confirm the effectiveness of this exercise therapy in the future. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022324824. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu