| Abstrakt: |
Objectives: Segmenting the prostate from magnetic resonance images plays an important role in prostate cancer diagnosis and in evaluating the treatment response. However, the lack of a clear prostate boundary, heterogeneity of prostate tissue, large variety of prostate shape and scarcity of annotated training data makes automatic segmentation a very challenging task. In this work, we proposed a novel two stage segmentation method to automatically segment prostate to support accurate and reproducible results with multisite and multivendor dataset. In the proposed method, we use the combination U-Net with residual blocks. Methods: The proposed method comprises two stage neural network, first is 2D U-Net, used find the approximate location of prostate, the second is the combination of U-Net and Res-Net used for accurate segmentation of prostate. The network was trained on 116 patient datasets from three publicly available data sources. 80% of data is used for training, 10% for validation, and 10% for testing. The commonly used segmentation evaluation metrics Dice similarity coefficient (DSC), Sensitivity, and Specificity are used for quantitative evaluation of the network. Results: With the proposed method average DSC value of 93.8%, Sensitivity value of 94.6% and Specificity of 99.3% was achieved on test datasets. Conclusions: Our experimental results show that the segmentation accuracy can be improved significantly using two stage neural networks. [ABSTRACT FROM AUTHOR] |
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