Cellular Location of 'Liver--Specific' Antigen F.

Autor: Forster, M., Celio, M. R., Winterhalter, K. H., Binz, H.
Předmět:
Zdroj: Scandinavian Journal of Immunology; Dec1986, Vol. 24 Issue 6, p745-750, 6p
Abstrakt: Three mouse monoclonal antibodies against Type 1 murine 'liver-specific' antigen F and one rat monoclonal antibody against human antigen F were produced. These monoclonals recognize antigenic determinants common to Type 1 and type 2 mouse and human antigen F. By immunolabelting with β-galactosidase, antigen F could be demonstrated in the cytoplasm of hepatocytes, tubules of the kidney, and perikarya of neurons of the central nervous system. F antigens isolated from liver, kidney, and brain all have molecular weights of around 40,000. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index